Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

R(-)-2,10,11-Trihydroxy-N-propylnoraporphine hydrobromide

Unique Identifier:LOPAC 00267
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:BrC19H22NO3
Molecular Weight:371.12 g/mol
X log p:8.916  (online calculus)
Lipinksi Failures1
TPSA3.24
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:2
Canonical Smiles:Br.CCCN1CCc2cc(O)cc3c2C1Cc1ccc(O)c(O)c13
Class:Dopamine
Action:Agonist
Selectivity:DRD2

Found: 9 active | as graph: single | with analogs 1 2 3 4 5 6 7 8 9 Next >> 
Species: 4932
Condition: CIN2
Replicates: 2
Raw OD Value: r im 0.6827±0.0137179
Normalized OD Score: sc h 0.8199±0.0197484
Z-Score: -13.6374±0.151317
p-Value: 5.44825e-42
Z-Factor: 0.395459
Fitness Defect: 95.0133
Bioactivity Statement: Active
Experimental Conditions
Library:Lopac
Plate Number and Position:6|F6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.90 Celcius
Date:2005-12-07 YYYY-MM-DD
Plate CH Control (+):0.0395±0.00186
Plate DMSO Control (-):0.82±0.01296
Plate Z-Factor:0.9279
png
ps
pdf

DBLink | Rows returned: 3
5019
173603
6603798

internal high similarity DBLink | Rows returned: 4
LOPAC 01342 0.9187
LOPAC 00266 0.9375
SPE01500129 0.9490
LOPAC 00265 0.9812

active | Cluster 1444 | Additional Members: 3 | Rows returned: 2
LOPAC 00266 0.363636363636364
LOPAC 00265 0.358208955223881

Service provided by the Mike Tyers Laboratory